PUBLICATIONS
Dong S and Dimopoulos G (2023) Aedes
aegypti Argonaute 2 controls arbovirus infection and
host mortality. Nature Communications. Accepted for
Publication.
Carballar-Lejarazú R, Dong Y, Pham TB,
Tushar T, Corder RM, Mondal A, Sánchez C HM, Lee HF,
Marshall JM, Dimopoulos G, James AA. (2023) Dual
effector population modification gene-drive strains of
the African malaria mosquitoes, Anopheles gambiae
and Anopheles coluzzii. Proc Natl Acad Sci U S A.
120(29):e2221118120.
Belavilas-Trovas A, Tastsoglou S, Dong S, Kefi M,
Tavadia M, Mathiopoulos KD, Dimopoulos G. (2023) Long
non-coding RNAs regulate Aedes aegypti vector
competence for Zika virus and reproduction. PLoS Pathog.
19(6):e1011440.
Engdahl CS, Caragata EP, Tavadia M,
Dimopoulos G. (2023) Chromobacterium Biopesticide
Exposure Does Not Select for Resistance in Aedes
Mosquitoes. mBio. 14(2):e0048023.
Bui M, Dalla Benetta E, Dong Y, Zhao Y,
Yang T, Li M, Antoshechkin IA, Buchman A, Bottino-Rojas
V, James AA, Perry MW, Dimopoulos G, Akbari OS. (2023)
CRISPR mediated transactivation in the human disease
vector Aedes aegypti. PLoS Pathog.
19(1):e1010842.
Villegas LEM, Radl J, Dimopoulos G,
Short SM. Bacterial communities of Aedes aegypti
mosquitoes differ between crop and midgut tissues.
(2023) PLoS Negl Trop Dis. 17(3):e0011218.
Samuel GH, Pohlenz T, Dong Y, Coskun N, Adelman ZN,
Dimopoulos G, Myles KM. (2023) RNA interference is
essential to modulating the pathogenesis of
mosquito-borne viruses in the yellow fever mosquito
Aedes aegypti. Proc Natl Acad Sci U S A.
120(11):e2213701120.
Tikhe CV, Dimopoulos G. (2023) Phage Therapy
for Mosquito Larval Control: a Proof-of-Principle Study.
mBio. e0301722.
Engdahl CS, Tikhe CV, Dimopoulos G. (2022)
Discovery of novel natural products for mosquito
control. Parasit Vectors. 15(1):481.
Carr AL, Rinker DC, Dong Y, Dimopoulos G, Zwiebel LJ.
Transcriptome profiles of Anopheles gambiae harboring
natural low-level Plasmodium infection reveal adaptive
advantages for the mosquito. Sci Rep. 2021 Nov
19;11(1):22578. doi: 10.1038/s41598-021-01842-x. PMID:
34799605; PMCID: PMC8604914.
Simões ML, Dong Y, Mlambo G
and Dimopoulos G (2022)
C-type lectin 4 regulates broad-spectrum
melanization-based refractoriness to malaria parasites.
PLoS Biology, 20(1):e3001515.
Tikhe CV, Cardoso-Jaime V, Dong S, Rutkowski N,
Dimopoulos G. (2022) Trypsin-like Inhibitor Domain
(TIL)-Harboring Protein Is Essential for Aedes
aegypti Reproduction. Int J Mol Sci. 23(14):7736.
Dong Y, Dong S,
Dizaji NB, Rutkowski N, Pohlenz T, Myles K, Dimopoulos
G. (2022) The Aedes aegypti siRNA pathway mediates
broad-spectrum defense against human pathogenic viruses
and modulates antibacterial and antifungal defenses.
PLoS Biol. 20(6):e3001668. doi:
10.1371/journal.pbio.3001668.
Pereira AE, Huynh MP, Paddock KJ, Ramirez JL,
Caragata EP, Dimopoulos G, Krishnan HB, Schneider SK,
Shelby KS, Hibbard BE. (2022) Chromobacterium Csp_P
biopesticide is toxic to larvae of three Diabrotica
species including strains resistant to Bacillus
thuringiensis. Sci Rep. 12(1):17858.
Arora G, Sajid A, Chuang YM, Dong Y, Gupta A, Gambardella K, DePonte K,
Almeras L, Dimopoulos G, and Fikrig E (2021)
Immunomodulation by mosquito salivary protein AgSAP
contributes to early host infection by Plasmodium. mBio,
Accepted for publication.
Dong S, Ye Z, Tikhe CV, Tu Z, Zwiebel J, Dimopoulos G. (2021) Pleiotropic
odorant-binding proteins promote Aedes aegypti
reproduction and flavivirus transmission. mBIO,
e0253121. doi: 10.1128/mBio.02531-21.
Accoti A, Springer Engdahl C,
Dimopoulos G (2021)
Discovery of novel entomopathogenic
fungi for mosquito-borne disease control. Front. Fungal
Biol. 2:637234. doi: 10.3389/ffunb.2021.637234.
MacLeod HJ, Dimopoulos G, Short SM (2021). Larval Diet Abundance
Influences Size and Composition of the Midgut Microbiota
of Aedes aegypti Mosquitoes. Front Microbiol.
12:645362. doi: 10.3389/fmicb.2021.645362. PMID:
34220739; PMCID: PMC8249813.
Angleró-Rodríguez YI, Tikhe CV, Kang S, Dimopoulos G (2021). Aedes aegypti
Toll pathway is induced through dsRNA sensing in
endosomes. Dev Comp Immunol. 122:104138. doi:
10.1016/j.dci.2021.104138. Epub 2021 May 20. PMID:
34022257.
Smith DFQ, Camacho E, Thakur R, Barron AJ, Dong Y,
Dimopoulos G, Broderick NA, Casadevall A. (2021)
Glyphosate inhibits melanization and increases
susceptibility to infection in insects. PLoS Biol.
19(5):e3001182. doi: 10.1371/journal.pbio.3001182. PMID:
33979323; PMCID: PMC8115815.
Caragata EP, Otero LM, Tikhe CV, Barrera
R, Dimopoulos G (2021) Microbial Diversity of
Adult Aedes aegypti and Water Collected from
Different Mosquito Aquatic Habitats in Puerto Rico.
Microbial Ecol,
doi: 10.1007/s00248-021-01743-6. Epub ahead of print.
PMID: 33860847.
Wang M, An Y, Dong S, Feng Y, Gao L, Wang
P, Dimopoulos G, Tang H, Wang
J (2021)
Glucose-mediated proliferation of a gut commensal bacterium promotes
Plasmodium infection by increasing mosquito midgut
pH. Cell Reports,
35(3):108992. doi: 10.1016/j.celrep.2021.108992.
Kwon H, Simões ML, Reynolds RA, Dimopoulos G, Smith RC.
(2021) Additional Feeding Reveals Differences in Immune
Recognition and Growth of Plasmodium Parasites in
the Mosquito Host. mSphere. 6(2):e00136-21.
Dou Z, Madan A, Carlson JS, Chung J, Spoleti T,
Dimopoulos G, Cammarato A, Mittal R. (2021)
Acoustotactic response of mosquitoes in untethered
flight to incidental sound. Sci Rep. 11(1):1884.
Kormos A, Lanzaro GC, Bier E, Dimopoulos G. Marshall JM,
Pinto J, Aguiar Dos Santos A, Bacar A, Sousa Pontes
Sacramento Rompão H, James AA. (2020) Application of the
Relationship-Based Model to Engagement for Field Trials
of Genetically Engineered Malaria Vectors. Am J Trop Med
Hyg. doi: 10.4269/ajtmh.20-0868.
Tripathi AK, Mlambo G, Kanatani S, Sinnis P, Dimopoulos
G. Plasmodium falciparum Gametocyte Culture and
Mosquito Infection Through Artificial Membrane Feeding.
(2020) J Vis Exp. (161).
Rutkowski N, Dong Y, and Dimopoulos G. (2020)
Field-deployable
molecular diagnostic platform for
arbovirus detection in
Aedes aegypti.
Parasites & Vectors 13, 489.
MacLeod H, Dimopoulos G. (2020) Detailed
analyses of Zika virus tropism in
Culex
quinquefasciatus
reveal systemic refractoriness. mBIO, 11, 4
e01765-20
DOI: 10.1128/mBio.
Dong Y, Simões ML, and Dimopoulos G (2020)
Versatile transgenic multi-stage effector-gene
combinations for Plasmodium falciparum suppression in
Anopheles. Science Advances 6: eaay5898.
Dong S, Fu X, Dong
Y, Simões ML, Zhu J,
Dimopoulos G (2020) Broad spectrum immunomodulatory
effects of Anopheles gambiae microRNAs and their use for
transgenic suppression of Plasmodium. PLoS Pathogens
16(4):e1008453.
Fu X, Liu P, Dimopoulos G, Zhu J (2020) Dynamic mRNA-mRNA
interactions coordinate gene expression in adult
Anopheles gambiae PLoS Genet 16(4):e1008765.
Caragata EP, Otero LM, Carlson JS, Dizaji NB, Dimopoulos G (2020) A
non-live preparation of Chromobacterium sp. Panama
(Csp_P) is a highly effective larval mosquito
biopesticide. Applied Environmental Microbiology
AEM.00240-20
Yang J, Schleicher TR, Dong Y, Park HB, Lan J, Cresswell P, Crawford J,
Dimopoulos G*, Fikrig E*. (2020) Disruption of mosGILT
in Anopheles gambiae impairs ovarian development and
Plasmodium infection. J Exp Med. 217(1). pii: e20190682.
*joint corresponding authors
Carlson JS., Short, S, Anglero-Rodriguez YI.,
Dimopoulos G. (2019)
Larval exposure to bacteria
modulates arbovirus infection and immune gene expression
in adult Aedes
aegypti.
Dev Comp Immunol. 104:103540.
Dong S, Kang S,
Dimopoulos
G. (2019) Identification of anti-flaviviral drugs
with mosquitocidal and anti-Zika virus activity in
Aedes aegypti. PLoS Negl Trop Dis.
13(8):e0007681.
Barrows NJ, Anglero-Rodriguez Y, Kim B, Jamison SF, Le Sommer C, McGee CE,
Pearson JL, Dimopoulos G, Ascano M, Bradrick SS,
Garcia-Blanco MA. (2019) Dual roles for the ER membrane
protein complex in flavivirus infection: viral entry and
protein biogenesis. Sci Rep. 9(1):9711.
Chuang YM, Freudzon M, Yang J, Dong Y,
Dimopoulos G, Fikrig E. (2019)
Anopheles gambiae Lacking AgTRIO
Inefficiently Transmits Plasmodium berghei to
Mice. Infect Immun.
87(9).
Caicedo PA, Serrato IM, Sim S, Dimopoulos G, Coatsworth H, Lowenberger C,
Ocampo CB (2018) Immune response-related genes
associated to blocking midgut dengue virus infection in
Aedes aegypti strains that differ in susceptibility
Insect Sci. doi: 10.1111/1744-7917.12573.
Schleicher TR, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, Graham
M, Mlambo G, Tripathi AK, Li Y, Cresswell P, Sinnis P,
Dimopoulos G, Fikrig E. (2018) A mosquito salivary gland
protein partially inhibits Plasmodium sporozoite cell
traversal and transmission. Nat Commun. 9(1):2908.
Saraiva R, Fang J., Kang S., Anglero-Rodriguez Y., Dong Y., Dimopoulos G.
(2018) Aminopeptidase secreted by Chromobacterium sp.
Panama inhibits dengue virus infection by degrading the
E protein. PLoS Negl. Trop. Dis. 12, e0006443.
doi:10.1371/journal.pntd.0006443.
Short SM., van Tol S., McLeod HJ., Dimopoulos G. (2018) Hydrogen cyanide
produced by the soil bacterium Chromobacterium sp.
Panama contributes to mortality in Anopheles gambiae
mosquito larvae. Sci Rep. 8(1):8358. doi:
10.1038/s41598-018-26680-2.
Taracena ML., Rojas VB., Talyuli OAC., Walter-Nuno AB., Oliveira JHM.,
Angleró-Rodriguez YI., Dimopoulos G., Oliveira PL.,
Paiva-Silva GO. (2017) Regulation of midgut cell
proliferation impacts Aedes aegypti susceptibility to
dengue virus. PLoS NTD 12(5):e0006498.doi:
10.1371/journal.pntd.0006498.
Pike A, Dimopoulos G. (2018) Genetic modification of Anopheles stephensi
for resistance to multiple Plasmodium falciparum strains
does not influence susceptibility to o’nyong’nyong virus
or insecticides, or Wolbachia-mediated resistance to the
malaria parasite. PLoS One 13(4):e0195720. doi:
10.1371/journal.pone.0195720.
Dragovic SM, Agunbiade TA, Freudzon M, Yang J, Hastings AK, Schleicher T,
Zhou X, Craft S, Chuang YM, Gonzalez F, Li Y, Hrebikova
G, Tripathi A, Mlambo G, Almeras L, Ploss A, Dimopoulos
G, and Fikrig E (2018) TRIO, a protein in Anopheles
saliva, elicits immunity against Plasmodium infection in
mice. Cell Host & Microbe 23(4):523-535.e5. doi:
10.1016/j.chom.2018.03.008.
Short SM, van Tol S, Smith B, Dong Y and Dimopoulos G. (2018) The mosquito
adulticidal Chromobacterium sp. Panama causes
transgenerational impacts on fitness parameters and
elicits xenobiotic gene responses. Parasit Vectors.
11(1):229. doi: 10.1186/s13071-018-2822-8.
Saraiva RG, Huitt-Roehl CR, Tripathi A, Cheng Y, Bosch J, Townsend CA,
Dimopoulos G. (2018) Chromobacterium spp. mediate their
anti-Plasmodium activity through secretion of the
histone deacetylase inhibitor romidepsin. Sci Rep. 8,
6176. doi:10.1038/s41598-018-24296-0.
Kefi M, Mavridis K, Simões ML, Dimopoulos G, Siden-Kiamos I, Vontas J.
(2018) New rapid one-step PCR diagnostic assay for
Plasmodium falciparum infective mosquitoes. Sci Rep.
8(1):1462.
Dong Y, Simões ML, Marois E, Dimopoulos G. (2018) CRISPR/Cas9 -mediated
gene knockout of Anopheles gambiae FREP1 suppresses
malaria parasite infection. PLoS Pathogens 8;14(3).
Anglero-Rodriguez YI, Talyuli OAC, Blumberg BJ, Kang S, Demby C, Shields
A, Carlson J, Jupatanakul N, Dimopoulos G. (2017) An
Aedes aegypti-associated fungus increases susceptibility
to dengue virus by modulating gut trypsin activity.
eLIFE, 6. pii: e28844. doi: 10.7554/eLife.28844.
Anglero-Rodriguez YI, MacLeod HJ, Kang S, Carlson J, Jupatanakul N,
Dimopoulos G. (2017) Aedes aegypti molecular responses
to Zika virus infection, and modulation of infection by
the Toll and Jak/Stat immune pathways and virus host
factors. Frontiers Microbiol., 8:2050. doi:
10.3389/fmicb.2017.02050.
Simoes ML, Mlambo G, Tripathi A, Dong Y, Dimopoulos G. (2017)
Immune-regulation of Plasmodium is Anopheles
species-specific and infection intensity-dependent.
mBIO, 8(5). pii: e01631-17.
Pike A, Dong Y, Dizaji NB, Gacita A, Mongodin EF, Dimopoulos G. (2017)
Changes in the microbiota cause genetically modified
Anopheles to spread in a population. Science
357(6358):1396-1399.
Short SM, Mongodin EF, MacLeod HJ, Talyuli OAC, Dimopoulos G. (2017) Amino
acid metabolic signaling influences Aedes aegypti midgut
microbiome variability. PLoS Negl Trop Dis.
11(7):e0005677.
Fu X, Dimopoulos G, Zhu J. (2017) Association of microRNAs with Argonaute
proteins in the malaria mosquito Anopheles gambiae after
blood ingestion. Sci Rep. 7(1):6493.
Tangsongcharoen C, Jupatanakul N, Promdonkoy B, Dimopoulos G, Boonserm P.
(2017) Molecular analysis of Culex quinquefasciatus
larvae responses to Lysinibacillus sphaericus Bin toxin.
PLoS One 12(4):e0175473.
Jupatanakul N, Sim S, Angleró-Rodríguez YI, Souza-Neto J, Das S, Poti KE,
Rossi SL, Bergren N, Vasilakis N and Dimopoulos G (2017)
Engineered Aedes aegypti JAK/STAT pathway-mediated
immunity to dengue virus. PLOS NTD 11(1):e0005187.
Amarante A, Jupatanakul J, de Abreu da Silva IC, Carneiro VC, Vicentino
ARR, Dimopolous G, Talyuli OAC, Fantappie MR (2017) The
DNA chaperone HMGB1 potentiates the transcriptional
activity of Rel1A in the mosquito Aedes aegypti. Insect
Biochem Mol Biol. 80:32-41.
Ward AM, Calvert ME, Read LR, Kang S, Levitt BE, Dimopoulos G, Bradrick
SS, Gunaratne J, Garcia-Blanco MA (2016) Emerging role
of lipid droplets in Aedes aegypti immune response
against bacteria and Dengue virus. Sci Rep. 6:34379.
Falckenhayn C, Carneiro VC, de Mendonça Amarante A, Schmid K, Hanna K,
Kang S, Helm M, Dimopoulos G, Fantappié MR, Lyko F
(2016) Comprehensive DNA methylation analysis of the
Aedes aegypti genome. Sci Rep.;6:36444.
Simões ML, Dong Y, Hammond A, Hall A, Crisanti A, Nolan T, Dimopoulos G.
(2016) The Anopheles FBN9 immune factor mediates
Plasmodium species-specific defense through transgenic
fat body expression. Dev Comp Immunol. pii:
S0145-305X(16)30290-7.
Angleró-Rodríguez YI, Blumberg BJ, Dong Y, Sandiford SL, Pike A, Clayton
AM, Dimopoulos G (2016) A natural Anopheles-associated
Penicillium chrysogenum enhances mosquito susceptibility
to Plasmodium infection. Sci. Rep. 6:34084.
Dennison NJ, Saraiva RJ, Cirimotich CM, Mlambo G, Mongodin EF, Dimopoulos
G (2016) Functional genomic analyses of Enterobacter,
Anopheles and Plasmodium reciprocal interactions that
impact vector competence. Malar J. 2016 Aug
22;15(1):425.
Barletta AB, Alves LR, Silva MC, Sim S, Dimopoulos G, Liechocki S,
Maya-Monteiro CM, Sorgine MH (2016) Emerging role of
lipid droplets in Aedes aegypti immune response against
bacteria and Dengue virus. Sci Rep. 6:19928.
Mesquita RD et al. (2015) Genome of Rhodnius prolixus, an insect vector of
Chagas disease, reveals unique adaptations to
hematophagy and parasite infection. Proc Natl Acad Sci U
S A 112(48):14936-14941.
Bottino-Rojas V, Talyuli OA, Jupatanakul N, Sim S, Dimopoulos G, Venancio
TM, Bahia AC, Sorgine MH, Oliveira PL, Paiva-Silva GO.
(2015) Heme Signaling Impacts Global Gene Expression,
Immunity and Dengue Virus Infectivity in Aedes aegypti.
PLoS One 10(8):e0135985.
Zhang G, Niu G, Franca CM, Dong Y, Wang X, Butler NS, Dimopoulos G, Li J.
(2015) Anopheles Midgut FREP1 Mediates Plasmodium
Invasion. J Biol Chem. 290(27):16490-501.
Sandiford SL, Dong Y, Pike A, Blumberg BJ, Bahia AC and Dimopoulos G
(2015) Cytoplasmic actin is an extracellular insect
immune factor which is secreted upon immune challenge
and mediates phagocytosis and direct killing of
bacteria, and is a Plasmodium antagonist. PLoS
Pathogens, 11(2):e1004631.
Dennison NJ, BenMarzouk-Hidalgo, OJ and Dimopoulos G (2015)
MicroRNA-regulation of Anopheles gambiae immunity to
Plasmodium falciparum infection and midgut microbiota.
Dev Comp Immunol. 49(1):170-8.
Ramirez JL, Short SM, Bahia AC, Saraiva RG, Dongn Y, Kang S, Tripathi T,
Mlambo G and Dimopoulos G (2014) Chromobacterium Csp_P
reduces malaria and dengue infection in vector
mosquitoes and has entomopathogenic and in vitro
anti-pathogen activities. PLoS Pathogens
10(10):e1004398.
Sanders, N, Sullivan D, Mlambo G, Dimopoulos G, Tripathi A (2014)
Gametocytocidal screen identifies novel chemical classes
with Plasmodium falciparum transmission blocking
activity. PLoS One, 9(8):e105817.
Kang S, Shields AR, Jupatanakul N and Dimopoulos G (2014) Suppressing
dengue-2 infection by chemical inhibition of Aedes
aegypti host factors. PLoS NTD, 7;8(8):e3084.
Pike A, Vadlamani A, Sandiford SL, Gacita A, Dimopoulos G (2014)
Characterization of the Rel2-regulated transcriptome and
proteome of Anopheles stephensi identifies new
anti-Plasmodium factors. Insect Biochem Mol Biol.
52C:82-93.
Bahia AC, Dong Y, Blumberg BJ, Mlambo G, Tripathi A, BenMarzouk-Hidalgo
OJ, Chandra R, and Dimopoulos G (2014) Exploring
Anopheles gut bacteria for Plasmodium blocking activity.
Environmental Microbiology 16(9):2980-94.
Jupatanakul N, Sim S, and Dimopoulos G (2014) Aedes aegypti ML and
Niemann-Pick type C family members are agonists of
dengue virus infection. Dev Comp Immunol. 43(1):1-9.
Blumberg JB, Trop S, Das S, Dimopoulos G (2013) Bacteria- and IMD
pathway-independent immune defenses against Plasmodium
falciparum in Anopheles gambiae. PLoS One,
10.1371/journal.pone.0072130.
Sim S, Jupatanakul N, Ramirez JL, Kang, S, Romero-Vivas CM, Mohammed H and
Dimopoulos G (2013) Transcriptomic profiling of diverse
Aedes aegypti strains reveals increased basal-level
immune activation in dengue virus-refractory populations
and identifies novel virus-vector molecular
interactions. PLoS NTD, 7(7):e2295.
Bian G, Joshi D, Dong Y, Lu P, Zhou G, Pan X, Xu Y, Dimopoulos G, Xi Z
(2013) Wolbachia Invades Anopheles stephensi Populations
and Induces Refractoriness to Plasmodium Infection.
Science, 340(6133):748-751.
Clayton AM, Cirimotich C, Dong, Y and Dimopoulos G (2013) Caudal is a
negative regulator of the Anopheles Imd pathway that
controls resistance to Plasmodium falciparum infection.
Dev Comp Immunol. 39(4):323-332.
Dong Y, Cirimotich C, Pike A, Chandra R and Dimopoulos G (2012) Anopheles
NF-?B -regulated splicing factors direct
pathogen-specific repertoires of the hypervariable
pattern recognition receptor AgDscam. Cell Host &
Microbe 12, 521–530.
Chen Y, Dong Y, Sandiford S and Dimopoulos G Transcriptional mediators Kto
and Skd are involved in the regulation of the IMD
pathway and anti-Plasmodium defense in Anopheles
gambiae. (2012) PLoS ONE;7(9):e45580.
Garver LS, Bahia AN, Das S, Souza-Neto J, Shiao J, Dong Y and Dimopoulos G
(2012) Anopheles Imd pathway factors and effectors in
infection intensity-dependent anti-Plasmodium action.
PLoS Pathogens. PLoS Pathogens 8(6): e1002737.
Sim S, Ramirez JL and Dimopoulos G (2012) Reciprocal interactions between
the dengue virus and Aedes aegypti salivary gland and
chemosensory apparatus influences vector competence.
PLoS Pathogens. 8(3):e1002631.
Ramirez LJ, Souza-Neto J, Cosme RT, Rovira J, Ortiz A, Pascale JM and
Dimopoulos G (2012) Reciprocal Tripartite Interactions
between the Aedes aegypti Midgut Microbiota, Innate
Immune System and Dengue Virus Influences Vector
Competence. PLoS Neglected Trop Dis. 6(3):e1561.
Gomulski L, Dimopoulos G, Xi Z, Gabrieli P, Scolari P, Siciliano P,
Malacrida AR, Gasperi G (2012) Changes in gene
expression related to maturation and mating in male and
female medfly, Ceratitis capitata. PLoS One.
7(1):e30857.
Dong Y, Morton JC Jr, Ramirez JL, Souza-Neto J and Dimopoulos G (2012) The
entomopathogenic fungus Beauveria bassiana activate Toll
and JAK-STAT pathway controlled effector genes and
anti-dengue activity in Aedes aegypti. Insect Biochem. &
Mol. Biol. 42(2):126-32.
Dong Y, Das S, Cirimotich CM, Souza-Neto J, McLean K and Dimopoulos G
(2011) Engineered Anopheles immunity to Plasmodium
infection. PLoS Pathogens 7(12): e1002458.
Zou Z, Souza-Neto JA, Xi Z, Kokoza V, Shin SW, Dimopoulos G, and Raikhel
AS (2011) Transcriptome analysis of Aedes aegypti
transgenic mosquitoes with altered immunity. PLoS
Pathogens. 7(11):e1002394.
Cirimotich CM, Dong Y, Clayton AM, Sandiford SL, Souza-Neto JA, Mulenga M,
and Dimopoulos G (2011) Natural microbe-mediated
refractoriness to Plasmodium infection in Anopheles
gambiae. Science 332: 855-858.
Das S., Radtke A., Choi YJ., Mendes A., Valenzuela J. and Dimopoulos G
(2010) The salivary gland transcriptome of Anopheles
gambiae and its implication in blood feeding. BMC
Genomics 11:566.
Bartholomay LC, Waterhouse RM, Mayhew GF, Campbell CL, Michel K, Zou Z,
Ramirez JL, Das S, Alvarez K, Arensburger P, Bryant P,
Chapman SB, Dong Y, Erickson SM, Karunaratne SHPP,
Kokoza V, Kodira CD, Pignatelli P, Shin SW,
Vanlandingham DL, Atkinson PW, Birren B, Christophides
GK, Clem RJ, Hemingway J, Higgs S, Megy K, Ranson H,
Zdobnov EM, Raikhel AS, Christensen BM, Dimopoulos G,
and Muskavitch MAT (2010) Pathogenomics of Culex
quinquefasciatus and meta-analysis of infection
responses to diverse Pathogens. Science 330: 88-90.
Arensburger P, Megy K, Waterhouse R, Abrudan J, Amedeo P, Antelo B,
Bartholomay L, Bidwell S, Caler E, Camara F, Campbell
CL, Campbell KS, Casola C, Castro MT, Chandramouliswaran
I, Chapman SB, Christley S, Costas J, Eisenstadt E,
Feschotte C, Fraser-Liggett C, Guigo R, Haas B, Hammond
M, Hansson BS, Hemingway J, Hill SR, Howarth C, Ignell
R, Kennedy RC, Kodira CD, Lobo NF, Mao C, Mayhew G,
Michel K, Mori A, Liu N, Naveira H, Nene V, Nguyen N,
Pearson MD, Pritham EJ, Puiu D, Qi Y, Ranson H, Ribeiro
JMC, Robertson HM, Severson DW, Shumway M, Stanke M,
Strausberg MR, Sun C, Sutton G, Tu Z, Tubio JMC, Unger
MF, Vanlandingham VL, Vilella AJ, White O, White JR,
Wondji CS, Wortman J, Zdobnov EM, Birren B, Christensen
BM, Collins FH, Cornel A, Dimopoulos G, Hannick LI,
Higgs S, Lanzaro G, Lee N, Muskavitch MAT, Raikhel A,
Atkinson P (2010) Sequencing of Culex quinquefasciatus
establishes a platform for mosquito comparative
genomics. Science 330: 86-88.
Aguilar R, Simard F, Kamdem C, Shields T, Glass GE, Garver LS, and
Dimopoulos G (2010) Genome-wide analysis of
transcriptomic divergence between laboratory colony and
field Anopheles gambiae mosquitoes of the M and S
molecular forms. Insect Mol Biol. 19(5):695-705.
Sim S and Dimopoulso G (2010) Dengue Virus Inhibits Immune Responses in
Aedes aegypti Cells. PLoS One, 18;5(5):e10678.
Ramirez JL and Dimopoulos G (2010) The Toll immune signaling pathway
control conserved anti-dengue defenses across diverse
Ae. aegypti strains and against multiple dengue virus
serotypes. Dev Comp Immunol. 34: 625-629.
Mair GR, Lasonder E, Garver LS, Franke-Fayard B, Carret CK, Wiegant J,
Dirks R, Dimopoulos G., Janse CJ, Waters AP. (2010) An
evolutionarily ancient P body controls zygote
development in the protozoan parasite Plasmodium. PLoS
Pathogens 12;6: e1000767.
Souza-Neto JA, Sim S, and Dimopoulos G (2009) Evolutionary conserved
function of the JAK-STAT pathway in anti-dengue defense.
Proc. Natl. Acad. Sci. USA. 106:17841- 6.
Dong Y., Manfredini F. and Dimopoulos G (2009) Implication of the Mosquito
Midgut
Microbiota in the Defense Against Malaria Parasites.
PLoS Pathogens, 5(5), e1000423.
Erickson SA, Xi Z, Mayhew GF, Ramirez JL, Aliota MT, Christensen BM,
Dimopoulos G (2009) Mosquito Infection Responses to
Developing Filarial Worms. PLoS Trop. Negl. Dis.
3(10):e529.
Baton LA, Robertson A, Warr E, Strand MR, and Dimopoulos G (2009)
Genome-wide transcriptomic profiling of Anopheles
gambiae hemocytes reveals pathogen-specific signatures
upon bacterial challenge and Plasmodium berghei
infection. BMC Genomics, 10(1):257.
Sessions OM, Barrows N,
Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers
MA, Ramirez JL, Dimopoulos G,
Yang PL,
Pearson JL,
and Garcia-Blanco MA. (2009) Discovery of Dengue
Virus Host Factors in Insects and Humans. Nature,
458(7241):1047-1050.
Dong, Y. and Dimopoulos, G (2009) Anopheles fibrinogen –related proteins
provide expanded pattern recognition capacity against
bacteria and malaria parasites. Biol Chem. 284(15):
9835–9844.
Garver LS., Dong Y., and Dimopoulos G (2009) Caspar control resistant to
Plasmodium falciparum in diverse Anopheline species.
PLoS Pathogens, Mar;5(3):e1000335.
Das S., and Dimopoulos G (2008) Molecular analysis of photic inhibition of
blood-feeding in Anopheles gambiae. BMC Physiology
16;8(1):23.
Abrantes A., Dimopoulos G., Grosso AR., do Rosário VE. and Silveira H.
(2008) Chloroquine mediated modulation of Anopheles
gambiae gene expression. PLoS ONE 2;3(7).
Xi Z., Ramirez JL., Dimopoulos G (2008) The Aedes aegypti Toll pathway
controls dengue virus infection. PLoS Pathog.4(7).
Gomulski LM., Dimopoulos G., Xi Z., Soares MB., Bonaldo MF., Malacrida
AR., Gasperi G. (2008) Gene discovery in an invasive
tephritid model pest species, the Mediterranean fruit
fly, Ceratitis capitata. BMC Genomics 2008, 9:248.
Warr, E., Das, S., Dong, Y., and Dimopoulos, G (2008) The Gram-Negative
Bacteria-Binding Protein gene family: Its role in the
innate immune system of Anopheles gambiae and in
anti-Plasmodium defense. Insect Mol. Biol., 17:39-51.
Garver, LS, Xi, Z and Dimopoulos, G (2008) Immunoglobulin superfamily
members play an important role in the mosquito immune
system, Dev. & Comp. Immunol. 32:519-31.
Aguilar, R., Das, S., Dong, Y. and Dimopoulos, G (2007) Continuous
exposure to Plasmodium results in decreased
susceptibility and transcriptomic divergence of the
Anopheles gambiae immune system. BMC Genomics, 8:451.
Waterhouse, RM, Kriventseva, EV, Meister, S, Xi, Z, Alvarez, KV,
Bartholomay, LC, Barillas-Mury, C, Bian, G, Blandin, S,
Christensen, BM, Dong, Y, Jiang, H, Kanost, MR, Koutsos,
AC, Levashina, EA, Li, J, Ligoxygakis, P, MacCallum, RM,
Mayhew, GF, Mendes, A, Michel, K, Osta, MA, Paskewitz,
S, Shin SW, Vlachou, D, Wang, L, Wei, W, Zheng, L, Zou,
Z, Severson, DW, Raikhel, AS, Kafatos, FC, Dimopoulos,
G, Zdobnov, EM, Christophides, GK (2007) Evolutionary
dynamics of immune-related genes and pathways in disease
vector mosquitoes. Science, 316:1738-1743.
Nene, V, Wortman, JR, Lawson, D, Haas, B, Kodira, C, Tu, ZJ, Loftus, B,
Xi, Z, Megy, K, Grabherr, M, Ren, Q, Zdobnov, EM, Lobo,
NF, Campbell, KS, Brown, SE, Bonaldo, MF, Zhu, J,
Sinkins, SP, Hogenkamp, DG, Amedo, P, Arsenburger, P,
Atkinson, PW, Bidwell, S, Biedler, J, Birney, E,
Bruggner, RV, Costas, J, Coy, MR, Crabtree, J, Crawford,
M, Debruyn, B, Decaprio, D, Eiglmeier, K, Eisenstadt, E,
El-Dorry, H, Gelbart, WM, Gomes, SL, Hammond, M,
Hannick, LI, Hogan, JR, Holmes, MH, Jaffe, D, Johnston,
SJ, Kennedy, RC, Koo H, Kravitz, S, Kriventseva, EV,
Kulp, D, Labutti, K, Lee, E, Li S, Lovin, DD, Mao, C,
Mauceli, E, Menck, CF, Miller, JR, Montgomery, P, Mori,
A, Nascimento, AL, Naveira, HF, Nusbaum, C, O'leary, SB,
Orvis, J, Pertea, M, Quesneville, H, Reidenbach, KR,
Rogers, YH, Roth, CW, Schneider, JR, Schatz, M, Shumway,
M, Stanke, M, Stinson, EO, Tubio, JM, Vanzee, JP,
Verjovski-Almeida, S, Werner, D, White, O, Wyder, S,
Zeng, Q, Zhao, Q, Zhao, Y, Hill, CA, Raikhel, AS,
Soares, MB, Knudson, DL, Lee ,NH, Galagan, J, Salzberg,
SL, Paulsen, IT, Dimopoulos, G, Collins, FH, Bruce, B,
Fraser-Liggett, CM, Severson, DW. (2007) Genome sequence
of Aedes aegypti, a major arbovirus vector. Science,
316:1718-1723.
Warr, E, Aguilar, R, Dong, Y. and Dimopoulos, G (2007) Transcriptome and
proteome dissection of the Anopheles gambiae midgut. BMC
Genomics, 8:37.
Warr, E, Lambrechts, L, Bourgouin C, Koella, J, and Dimopoulos, G (2006)
Melanization of Sephadex Beads in Anopheles gambiae is
controlled by anti-Plasmodium immune factors. Insect
Biochemistry and Molecular Biology, 36:769-778
Mair G, Braks J.A.M, Garver L, Wiegant J.K.A.G, Hall Dirks, R.W, Khan S.M,
Dimopoulos, G, Janse C.J, Waters A.P. (2006) Regulation
of sexual development of Plasmodium by translational
repression. Science, 313(5787):667-669.
Dong Y, Taylor H.E, and Dimopoulos, G (2006) AgDscam, a hyper variable
immunoglobulin domain containing receptor of the
Anopheles gambiae innate immune system. PLoS Biology 4:
e229.
Dong Y, Aguilar R, Xi Z, Warr E, Mongin E, and Dimopoulos, G (2006)
Anopheles gambiae immune responses to human and rodent
Plasmodium parasite species. PLoS Pathogens 6: 1-13.
Heard NA, Holmes CC, Stephens DA, Hand DJ and Dimopoulos, G (2005)
Bayesian Co-clustering of Anopheles Gene Expression Time
Series: A Study of Immune Defense Response To Multiple
Experimental Challenges. Proc Natl Acad Sci U S A
102:16939-16944.
Xu, XJ, Dong, Y, Abraham, EG, Kocan, A, Srinivasan, P, Sinden,
RE, Ribeiro, JMC, Jacobs-Lorena, M, Kafatos, FC,
and Dimopoulos, G. (2005) Transcriptome analysis of
Anopheles stephensi-Plasmodium berghei interactions. Mol
Biochem Parasitol. 142:76-87.
Both, M, Eckert, SE, Csukai, M, Dimopoulos, G, Spanu PD. (2005) Transcript
profiles of Blumeria graminis development during
infection reveal a cluster of genes that are potential
virulence determinants. Molecular Plant-Microbe
Interactions. 18(2):125-133.
Aguilar, R, Jedlicka, AE, Mintz, M, Mahairaki, V, Scott AL, and
Dimopoulos, G (2005) Global gene expression analysis of
Anopheles gambiae responses to microbial challenge.
Insect Biochem Mol Biol. ;35:709-719.
Abraham EG, Islam S, Srinivasan P, Ghosh AK, Valenzuela JG, Ribeiro LMC,
Kafatos FC, Dimopoulos, G and Jacobs-Lorena M. (2004)
Analysis of the Plasmodium and Anopheles transcriptional
repertoire during ookinete development and midgut
invasion. J Biol Chem. 279: 5573-5580.
Srinivasan P, Abraham EG, Ghosh AK, Valenzuela J, Ribeiro JMC, Dimopoulos,
G, Kafatos FC, Adams JH, Fujioka J and Jacobs-Lorena M.
(2004) Analysis of The Plasmodium and Anopheles
transcriptomes during oocyst differentiation. J Biol
Chem. 279: 5581-5587.
Wu MH, Dimopoulos, G, Mantalaris A, Varley J. (2003) The effect of
hyperosmotic pressure on the antibody production and
gene expression of GS-NS0 cell line. Biotechnol Appl
Biochem. Nov 13.
Kumar S, Christophides GK, Cantera R, Charles B, Soon HY, Meister P,
Dimopoulos, G, Kafatos FC, Barillas-Mury C. (2003) The
role of Reactive Oxygen Species (ROS) on Plasmodium
melanotic encapsulation in Anophele gambiae. Proc.
Natl. Acad. Sci. USA. 100: 14139- 14144.
Dessens, JT, Sidén-Kiamos, I, Jmendoza, J, Mahairaki, V, Khater, E,
Vlachou, D, Xu, JX, Kafatos, FC, Louis, C, Dimopoulos,
G. and Sinden, RE. (2003) SOAP, a novel malaria ookinete
protein involved in mosquito midgut invasion and oocyst
development. Mol Microbiol. 49:319-329.
Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass
C, Brey PT, Collins FH, Danielli A, Dimopoulos, G, et
al, (2002) Immunity-related genes and gene families in
Anopheles gambiae. Science 298:159-165.
Zdobnov EM, von Mering C, Letunic I, Torrents D, Suyama M, Copley RR,
Christophides GK, Thomasova D, Holt RA, Subramanian GM,
Mueller HM, Dimopoulos, G, etal, (2002) Comparative
genome and proteome analysis of Anopheles gambiae and
Drosophila melanogaster. Science 298: 149-159.
Dimopoulos, G, Christophides GK, Meister S, Schultz J, White KP,
Barillas-Mury C.and Kafatos FC. (2002) Genome expression
analysis of Anopheles gambiae: Responses to injury,
bacterial challenge and malaria infection. Proc. Natl.
Acad. Sci. USA. 99:8814-8819.
REVIEW ARTICLES
Arora G, Chuang YM, Sinnis P, Dimopoulos G, Fikrig E.
(2023) Malaria: influence of Anopheles mosquito saliva
on Plasmodium infection. Trends Immunol. 2023
Apr;44(4):256-265.
Cardoso-Jaime V, Tikhe CV, Dong S, Dimopoulos
G. The Role of Mosquito Hemocytes in Viral Infections.
Viruses. 2022 Sep 20;14(10):2088. doi:
10.3390/v14102088. PMID: 36298644; PMCID: PMC9608948.
Dong S, Dong Y, Simões ML, Dimopoulos G (2021) Mosquito
transgenesis for malaria control. Trend in Parasitology,
38(1):54-66.
Tikhe CV, Dimopoulos G. (2021) Mosquito antiviral immune
pathways. Dev Comp Immunol. 116:103964.
Dong S, Dimopoulos G. (2021) Antiviral Compounds for
Blocking Arboviral Transmission in Mosquitoes. Viruses.
13(1):108. doi: 10.3390/v13010108. PMID: 33466915;
PMCID: PMC7830659.
Caragata E, Dong S, Dong Y, Simões ML,
Tikhe CV,
Dimopoulos G. (2020) Prospects and Pitfalls:
Next-Generation Tools to Control Mosquito-transmitted
Disease. Annual Review of Microbiology. Accepted for
publication.
Dimopoulos G. (2019) Combining Sterile
and Incompatible Insect Techniques for Aedes albopictus
Suppression. Trends Parasitol. 35(9):671-673.
Saraiva RG,
Dimopoulos
G. (2019) Bacterial natural products in the fight
against mosquito-transmitted tropical diseases. Nat Prod
Rep. doi:
10.1039/c9np00042a.
Caragata EP, Tikhe CV,
Dimopoulos G. (2019) Curious
entanglements: interactions between mosquitoes, their
microbiota, and arboviruses. Curr Opin Virol.37:26-36.
Simões ML, Caragata EP, Dimopoulos G. (2018) Diverse Host and Restriction
Factors Regulate Mosquito-Pathogen Interactions. Trends
Parasitol. 34(7):603-616.
Saraiva RG, Kang S, Simões ML, Angleró-Rodríguez YI, Dimopoulos G (2016)
Mosquito gut antiparasitic and antiviral immunity. Dev
Comp Immunol. 64:53-64.
Simoes ML, and Dimopoulos G. (2015) A mosquito mediator of
parasite-induced immune priming. Trends Parasitol. pii:
S1471-4922(15)00168-3.
Jupatanakul N, Sim S, Dimopoulos G. (2014) The insect microbiome modulates
vector competence for arboviruses. Viruses,
6(11):4479-504.
Sim S., Jupatanakul N., Dimopoulos G. (2014) Mosquito Immunity against
Arboviruses. Viruses, 6(11):4479-504.
Dennison NJ, Jupatanakul N, Dimopoulos G. (2014) The mosquito microbiota
influences vector competence for human pathogens. Curr.
Opin. Insect Sci. 3, 6–13.
Clayton AM, Dong Y and Dimopoulos G (2014) The Anopheles innate immune
system in the defense against malaria infection. J
Innate Immunity. 6(2):169-81.
Cirimotich CM, Ramirez JL and Dimopoulos G (2011) Native microbiota shape
insect vector competence for human pathogens. Cell Host
& Microbe. 10(4):307-10.
Cirimotich CM, Dong Y, Garver LS, Sim S, Dimopoulos G. (2009) Mosquito
immune defenses against Plasmodium infection. Dev Comp
Immunol. 34(4):387-95.
Sim S, Ramirez JL, and Dimopoulos G. (2009) Molecular discrimination of
mosquito vectors and their pathogens. Expert Review of
Molecular Diagnostics. 9(7):757-65.
Ramirez JL., Garver L., and Dimopoulos G. (2008) Challenges and Approaches
for Mosquito Targeted Malaria Control. Curr. Mol.
Medicine. 9(2):116-30.
Baton L, Garver L, Xi Z and Dimopoulos G. (2008) Functional genomics
studies on the innate immunity of disease vectors.
Insect Science, 15:15-27.
Dimopoulos G. (2007) Building a better mosquito: identifying the genes
enabling malaria and dengue fever resistance in A.
gambiae and A. aegypti mosquitoes. J Vis Exp. (5):233.
Baton, L, Garver, L.S, Xi, Z, and Dimopoulos, G. (2007) Functional
genomics studies on the innate immunity of disease
vectors. Insect Science. 15:15-27.
Baton, L, Dong, Y, Li, J. and Dimopoulos, G. (2006) Variation in mosquito
immunity to Plasmodium. Proceedings of the 11th
International Congress of Parasitology.
Aguilar R, Dong Y, Warr E and Dimopoulos, G. (2005) Anopheles infection
responses: laboratory models versus field malaria
transmission systems. Acta Tropica 95(3):285-291.
Dimopoulos, G. (2003) Insect immunity and its implication in
mosquito-malaria interactions.
Microreview Cell Microbiol.5: 3-14.
BOOKS & BOOK CHAPTERS
Arthropod vector: Controller of Disease Transmission (2017) Editors:
Stephen K. Wikel, Serap Aksoy, George Dimopoulos.
Elsevier.
Blumberg BJ, Short SM, Dimopoulos G. Employing the mosquito microflora for
disease control. In: Adelman ZN, editor. Genetic control
of malaria and dengue. San Diego, CA: Elsevier, 2015.
Sim S, Cirimotich CM, Ramirez JL, Souza-Neto JA, Dimopoulos G (2012)
Dengue Virus-Mosquito Interactions and Molecular Methods
of Vector Control. In Dengue and Dengue Hemorrhagic
Fever. 2nd Edition. Edited by Duane J Gubler, Jeremy
Farrar, Eng Ooi and Subhash Vasudevan. CABI. Under
editorial processing.
Pike AD, Cirimotich CM and Dimopoulos G (2012) Mosquito Fitness Impact of
Transgenic Immune Deployment. In Ecology of Vector Borne
Disease Control, 3rd Edition. Edited by Sander Koenraadt
and Willem Takken. Wageningen Academic Publishers.
Baton, L., Warr, E., Hoffman S. and Dimopoulos, G. (2007) Programmed cell
death during malaria parasite infection of the
vertebrate host and mosquito vector. In Programmed Cell
Death in Protozoa. Edited by José Manuel Pérez Martin.
Landes Bioscience, Springer.
Dimopoulos G (2008) Paperless Joy: Paperless Business & Lifestyle Design
with Information & Communication Technology. 1st
Edition, Digital Life Artist Inc.
Garver, L.S., Baton, L., and Dimopoulos, G. (2007) Mosquito Immunity to
the Malaria Parasite. In Insect Immunology. Edited by
Nancy Beckage. Elsevier.
Dimopoulos, G, Kafatos F.C, Waters A.P, Sinden R.E. (2002) Malaria
Parasites and the Anopheles Mosquito. In Chemical
Immunology Vol. 80 “Malaria Immunology“ 2nd ,pp. 27-49.
REVIEW ARTICLES
Caragata E,
Dong S, Dong Y, Simões ML, Tikhe CV,
Dimopoulos G. (2020) Prospects and Pitfalls:
Next-Generation Tools to Control Mosquito-transmitted
Disease. Annual Review of Microbiology. Accepted for
publication.
Dimopoulos G. (2019) Combining Sterile and Incompatible
Insect Techniques for Aedes albopictus Suppression.
Trends Parasitol. 35(9):671-673.
Saraiva RG,
Dimopoulos
G. (2019) Bacterial natural products in the fight
against mosquito-transmitted tropical diseases. Nat Prod
Rep. doi:
10.1039/c9np00042a.
Caragata EP, Tikhe CV,
Dimopoulos
G. (2019) Curious entanglements: interactions
between mosquitoes, their microbiota, and arboviruses.
Curr Opin Virol.37:26-36.
Simões ML, Caragata EP, Dimopoulos G.
(2018) Diverse Host and Restriction Factors Regulate
Mosquito-Pathogen Interactions. Trends Parasitol.
34(7):603-616.
Saraiva RG, Kang S, Simões ML,
Angleró-Rodríguez YI, Dimopoulos G (2016) Mosquito gut
antiparasitic and antiviral immunity. Dev Comp Immunol.
64:53-64.
Simoes ML, and Dimopoulos G. (2015) A
mosquito mediator of parasite-induced immune priming.
Trends Parasitol. pii: S1471-4922(15)00168-3.
Jupatanakul N, Sim S, Dimopoulos G.
(2014) The insect microbiome modulates vector competence
for arboviruses. Viruses, 6(11):4479-504.
Sim S., Jupatanakul N., Dimopoulos G.
(2014) Mosquito Immunity against Arboviruses. Viruses,
6(11):4479-504.
Dennison NJ, Jupatanakul N, Dimopoulos
G. (2014) The mosquito microbiota influences vector
competence for human pathogens. Curr. Opin. Insect Sci.
3, 6–13.
Clayton AM, Dong Y and Dimopoulos G
(2014) The Anopheles innate immune system in the defense
against malaria infection. J Innate Immunity.
6(2):169-81.
Cirimotich CM, Ramirez JL and
Dimopoulos G (2011) Native microbiota shape insect
vector competence for human pathogens. Cell Host &
Microbe. 10(4):307-10.
Cirimotich CM, Dong Y, Garver LS, Sim
S, Dimopoulos G. (2009) Mosquito immune defenses against
Plasmodium infection. Dev Comp Immunol. 34(4):387-95.
Sim S, Ramirez JL, and Dimopoulos G.
(2009) Molecular discrimination of mosquito vectors and
their pathogens. Expert Review of Molecular Diagnostics.
9(7):757-65.
Ramirez JL., Garver L., and Dimopoulos
G. (2008) Challenges and Approaches for Mosquito
Targeted Malaria Control. Curr. Mol. Medicine.
9(2):116-30.
Baton L, Garver L, Xi Z and Dimopoulos
G. (2008) Functional genomics studies on the innate
immunity of disease vectors. Insect Science, 15:15-27.
Dimopoulos G. (2007) Building a better
mosquito: identifying the genes enabling malaria and
dengue fever resistance in A. gambiae and A. aegypti
mosquitoes. J Vis Exp. (5):233.
Baton, L, Garver, L.S, Xi, Z, and
Dimopoulos, G. (2007) Functional genomics studies on the
innate immunity of disease vectors. Insect Science.
15:15-27.
Baton, L, Dong, Y, Li, J. and
Dimopoulos, G. (2006) Variation in mosquito immunity to
Plasmodium. Proceedings of the 11th International
Congress of Parasitology.
Aguilar R, Dong Y, Warr E and
Dimopoulos, G. (2005) Anopheles infection responses:
laboratory models versus field malaria transmission
systems. Acta Tropica 95(3):285-291.
Dimopoulos, G. (2003) Insect immunity
and its implication in mosquito-malaria interactions.
Microreview Cell Microbiol.5: 3-14.
BOOKS & BOOK CHAPTERS
Arthropod vector: Controller of Disease
Transmission (2017) Editors: Stephen K. Wikel, Serap
Aksoy, George Dimopoulos. Elsevier.
Blumberg BJ, Short SM, Dimopoulos G.
Employing the mosquito microflora for disease control.
In: Adelman ZN, editor. Genetic control of malaria and
dengue. San Diego, CA: Elsevier, 2015.
Sim S, Cirimotich CM, Ramirez JL,
Souza-Neto JA, Dimopoulos G (2012) Dengue Virus-Mosquito
Interactions and Molecular Methods of Vector Control. In
Dengue and Dengue Hemorrhagic Fever. 2nd Edition. Edited
by Duane J Gubler, Jeremy Farrar, Eng Ooi and Subhash
Vasudevan. CABI. Under editorial processing.
Pike AD, Cirimotich CM and Dimopoulos G
(2012) Mosquito Fitness Impact of Transgenic Immune
Deployment. In Ecology of Vector Borne Disease Control,
3rd Edition. Edited by Sander Koenraadt and Willem
Takken. Wageningen Academic Publishers.
Baton, L., Warr, E., Hoffman S. and
Dimopoulos, G. (2007) Programmed cell death during
malaria parasite infection of the vertebrate host and
mosquito vector. In Programmed Cell Death in Protozoa.
Edited by José Manuel Pérez Martin. Landes Bioscience,
Springer.
Dimopoulos G (2008) Paperless Joy:
Paperless Business & Lifestyle Design with Information &
Communication Technology. 1st Edition, Digital Life
Artist Inc.
Garver, L.S., Baton, L., and
Dimopoulos, G. (2007) Mosquito Immunity to the Malaria
Parasite. In Insect Immunology. Edited by Nancy Beckage.
Elsevier.
Dimopoulos, G, Kafatos F.C, Waters A.P,
Sinden R.E. (2002) Malaria Parasites and the Anopheles
Mosquito. In Chemical Immunology Vol. 80 “Malaria
Immunology“ 2nd ,pp. 27-49.
